Projekte der AG Biomedizinische Bildgebung

Komplexes Erleben und Verhalten erfordern, dass Hirnareale miteinander kommunizieren und dass diese Kommunikation flexibel und dynamisch ist. Wir untersuchen mit MR-Methoden (MRS, fMRT, DWI) und mathematischen Modellen, ob diese Flexibilität bei neuropsychiatrischen Erkrankungen (Depression, Multiple Sklerose) verändert ist.

Complex experiences and behaviors require that brain areas communicate with each other, and that this communication be flexible. Using MR-methods (i.e., MRS, fMRT, DWI) and mathematical models, we investigate whether this flexibility is altered in the presence of neuropsychiatric disorders (e.g., Depression, Multiple Sclerosis).

• Retest reliability of estimates of functional connectivity dynamics (FCD-retest)
• Functional Connectivity Dynamics in Major Depressive Disorder (FCD-MDD)
• Functional Connectivity Dynamics in Multiple Sclerosis (FCD-MS)
• Metabolic correlates of Functional Connectivity Dynamics (FCD-MRS)

Emotionen entstehen in einem Zusammenspiel vieler Hirnareale. Wir entwickeln Methoden zur Echtzeitidentifikation emotionaler kognitiver Zustände für zustandsabhängige Stimulation und Neurofeedback.

Emotions arise from the interplay of many brain areas. We develop methods for real-time identification of emotional and cognitive states for state-dependent stimulation and neurofeedback.

• Representations of phobic and conditioned stimuli (RESOPACS)
• Multidimensional scaling of emotional states (MuSES)
• Multivariate identification of mental states (MIMeS)
• Multivariate realtime identification of states (MRIS)
• State dependent stimulation (SDS)
• Neurofeedback of mental and emotional states (NOMES)