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Prof. Dr. Stefan Dove (im Ruhestand)

Dove
Außerordentlicher Professor

Prof. Dr. Stefan Dove

Gebäude CH, Zi. 03.1.88

Telefon  0941 943-4673
Telefax  0941 943-4820

E-Mail stefan.dove@ur.de


Publikationen


Forschungsschwerpunkte:

  • Computer-Aided Drug Research (Quantitative Structure-Activity Relationships, especially 3D-QSAR approaches, Molecular Modeling)
  • Structure-activity relationships and binding models of ligands of G-protein coupled receptors (GPCR homology models, docking, 3D-QSAR), in particular: agonists and antagonists of histamine-H2-, H4-, 5HT2A-, beta-adrenergic and  neuropeptide Y Y1-receptors, modeling of active receptor states
  • Inhibitors of receptor tyrosine kinases (modeling and structure-based design); grant from Deutsche Krebshilfe e.V. / Dr. Mildred Scheel Stiftung für Krebsforschung (2001 - 2005)
  • Inhibitors of bacterial hyaluronan lyases and human hyaluronidases (modeling and structure-based design)
  • Substituted nucleotides as inhibitors of bacterial and human adenylyl cyclases – modeling of ligand-enzyme interactions

Zusätzliche Forschungsinteressen:

  • Modeling and prediction of protein-protein interactions (e.g., of TIR domains)
  • Receptor theory


  1. Fakultät für Chemie und Pharmazie
  2. Institut für Pharmazie